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GCU BIO 322 Exam 2 2025 Questions and Answers Tuberculosis (TB) - ....ANSWER☑️☑️...-Infectious lung disease - used to be called consumption Tuberculosis (TB) causes - ....ANSWER☑️☑️...-Mycobacterium tuberculosis -> incubation period 2-8 weeks Decreased immune system -> high rate of co-infection with HIV Crowded living quarters; poverty; homelessness; substance abuse; decreased access to medical care/screening Tuberculosis (TB) signs and symptoms (active) - ....ANSWER☑️☑️...-Asymptomatic during early stages Cough that produces purulent sputum, develops slowly Night sweats, fatigue, fever/chills, pleurisy, weight loss, caseous necrosis (TB bacteria can resist lysosomal killing in a macrophage -> granulomatous tubercle of dead material and dormant bacilli after about ten days Tuberculosis (TB) signs and symptoms (systemic) - ....ANSWER☑️☑️...-Can affect any other organs (neurological deficits, meningitis, bone pain, urinary symptoms) Tuberculosis (TB) signs and symptoms (latent) - ....ANSWER☑️☑️...-Asymptomatic, very slow to progress, not noticed until advanced disease, granulomas (Ghon), coinfection with HIV (MC) increase risk of deactivation as well as cancer 1